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  1. Roberts, J.C.; Nagasawa, H.T.; Zera, R.T.; Fricke, R.F.; Goon, D.J. W.. Prodrugs of L-cysteine as protective agents against acetaminophen-induced hepatotoxicity. 2-(polyhydroxyalky)-and 2-(Polyacetoxyalky)-Thiazolidine-4(R)- Carboxylic Acids. Med Chem., 1987, 30, 1891-1896.
  2. Roberts, J.C.; Francetic, D.J.; Zera, R.T. L-cysteine prodrug protects against cyclophosphamide urotoxicity without compromising therapeutic activity. . Cancer Chemotherapy and Pharmacology1991, 28, 166-170.
  3. Roberts, J.C.; Francetic, D.J. Time course for the elevation of glutathione innumerous organs of L1210-bearing CDF1 mice given the L-cysteine prodrug, RibCys. Toxicology Letters, 1991, 59, 245-251.
  4. Roberts, J.C.; Francetic, D.J. Mechanisms of Chemoprotection by RibCys, a Thazolidine Prodrug of L-cysteine. Med. Chem, Res., 1991,1, 213-219.
  5. Roberts, J.C.; Charyulu, R. L.; Zera, R.T.; Nagasawa, H.T Protection Against Acetaminophen Hepatotoxicity by Ribose-Cysteine (RibCys). Pharmacology & Toxicology, 1992, 70, 281-285.
  6. Rowe, J.K.; Zera, R.T.; Madoff, R.D.; Fink, A.S.; Roberts, J.C.; Johnston, G.R.; Freeney, D.A.;Young, H.L.; Bubrick, M.P. Protective Effect of RibCys Following High-Dose Irradiation of the Rectosigmoid. Dis. Colon Rectum1993, 36(7), 681-687.
  7. Roberts, J.C.;Francetic, D.J.; Zera, R.T.Chemoprotection against Cyclophosphamide-Induced Urotoxicity: Comparison of Nine Thiol Protective Agents. AntiCancer Research, 1994, 14, 389-396.
  8. Carroll, M.P.; Zera, R.T.; Roberts, J.C.; Schlafmann, S.E.; Feeny, D.A.; Johnston, G.R.; West, M.A.; Bubrick, M.P. Efficacy of Radioprotective Agents in Preventing Small and Large Bowel Radiation Injury. Dis. Colon Rectum, 1995, 38(7), 716-722.
  9. Roberts, J.C.; Koch, K.E.; Detrick, S.R.; Warters, R.L.; Lubec G. Thiazolidine Prodrugs of Cysteamine and Cysteine as Radioprotective Agents. Radiation Research, 1995, 143, 203-213.
  10. Bantseev, V.; Bhardwaj, R.; Rathbun, W.; Nagasawa, H.T.; Trevithick, J.R.
    Antioxidants and Cataract: (Cataract Induction in Space Environment and Application to Terrestrial Aging Cataract).
    Biochem. Mol. Bio. Intl., 1997, 42, 1189-1197.
  11. Roberts, J.C.; Phaneuf, H.L.; Szakacs, J.G.; Zera, R.T.; Lamb, J.G.; Franklin, M.R. Differential Chemoprotection against Acetaminophen-Induced
    Hepatotoxicity by Latentiated L-Cysteines.
    Chem. Res. Toxicol., 199811, 1274-1282.
  12. Roberts, J.C.; Phaneuf, H.L.; Dominick, P.K.; Wilmore, B.H.; Cassidy, P.B. Biodistribution of [35S] – Cysteine and Cysteine Prodrugs: Potential Impact on Chemoprotection Strategies. J. Labelled Cpd. Radiopharm., 1999, all.riboceine.study1.51
  13. Lucus, A.M.; Henning G.; Dominick, P.K.; Whiteley, H.E.; Roberts, J.C.; Cohen, S.D. Ribose Cysteine Protects Against Acetaminophen-Induced Hepatic and
    Renal Toxicity.
    Toxicologic Pathology, 2000, 28(5), 697-704.
  14. Wilmore, B.H.; Cassidy, P.B.; Warters, R.L.; Roberts, J.C. Thiazolidine Prodrugs as Protective Agents against y-Radiation-Induced Toxicity and Mutagenesis in V79 Cells. J. Med. Chem., 44(16), 2661-2666.,, 44(16), 2661-2666.
  15. Lenarczyk, M.; Ueno, A.; Vannais, D.B.; Kraemer, S.; Kronenberg, A.; Roberts, J.C.; Tatsumi, K.; Hei, T.K.; Waldron, C.A. A. Comparative reaction rates of various antioxidants with ABTS radical cation – PubMed (nih.gov)Radiation Research
  16. Waldron, C.A.; Vannais, D.B.; Ueno A.M. . A role for long-lived radicals (LLR) in radiation-induced mutation and persistent chromosomal instability: counteraction by Ascorbate and Ribs but not DMSO. Mutation Research. 2004, 551-255-265.
  17. Lucas Slitt, A.M.; Dominick, P.K.; Roberts, J.C.; Cohen, S.D. Effect of Ribose Cysteine Pretreatment on Hepatic and Renal Acetaminophen Metabolite Formation and Glutathione Depletion. Basic Clin. Pharmacol. Toxicol 2005, 96(6), 487-94.
  18. Oz, H.S.; Chen, T.S.; Nagasawa, H Comparative efficacies of 2 cysteine prodrugs and a glutathione delivery agent in a colitis model. Translational Research 150(2), 122-129., 150(2), 122-129.
  19. Jurkowska, H.; Uchacz, T.; Roberts, J.; Wrobel, M. Potential therapeutic advantage of ribose-cysteine in the inhibition of astrocytoma cell proliferation Amino Acids2011, 41, 131-139.
  20. Walker R.B., Everette J.D Comparative reaction rates of various antioxidants with ABTS radical cation.J. Agric Food Chem., 2009:57:1156-1161.
  21. Heman-Ackah, S.E.; Juhn, S.K.; Huang, T.C.; Wiedmann, T.S Potential therapeutic advantage of ribose-cysteine in the inhibition of astrocytoma cell proliferation Otolaryngology-Head and Neck Surgery 2010, 143, 429-434
  22. Kader, T.; Porteous C.M.; Williams M.A.J.A.; Gieseg, S.P.; McCormick, S.P.A. Ribose-cysteine increases glutathione-based antioxidant status and reduces LDL in human lipoprotein(a) mice. Atherosclerosis2014, 237, 725-733.
  23. Saltman A.E. D-Ribose-L-cysteine supplementation enhances wound healing in a rodent model. Am J Surg2015, 210, 153-158.
  24. Falana B, Adeleke O, Orenolu M, Osinubi A, Oyewopo A. Effect of D-ribose-L-cysteine on aluminum induced testicular damage in male Sprague-Dawley rats. JBRA Assisted Reproduction2017, 21(2):94-100.
  25. Joseph D.B., Olayemi O.S., Falana B.A., Duru F.I.O. Osinubi A.A.A. D-Ribose-LCysteine Maintained Testicular Integrity in Rats Model (Rattus Novergicus) Exposed to X-Ray. Nuclear Medicine2017, (2)4:20-26.
  26. N’guessan B.B., Amponsah S.K., Dugbartey G.J., Awuah K.D., Dotse E., Aning A., Kukuia K.K.E., Asiedu-Gyekye I.J., Appiah-Opong R.In Vitro Antioxidant Potential and Effect of a GlutathioneEnhancer Dietary Supplement on Selected Rat Liver Cytochrome P450 Enzyme Activity. Evidence-Based Complementary and Alternative Medicine, 20182017, 7462839:8 pages.
  27. Awodele O, Badru W.A., Busari A.A., Kale O.E., Ajayi T.B., Udeh R.O. Emeka P.M. Toxicological evaluation of therapeutic and supra-therapeutic doses of Cellgevity® on reproductive function and biochemical indices in Wistar rats. BMC Pharmacology and Toxicology2017, 2018:19:68.
  28. Cukrov D., Newman T.A.C., Leask M., Leeke B., Sarogni P., Patimo A., Kline A.D., Krantz I.D., Horsfield J.A., Musio A. Toxicological evaluation of therapeutic and supra-therapeutic doses of Cellgevity® on reproductive function and biochemical indices in Wistar rats. Human Molecular Genetics2018, 2018:27:17:3002- 3011
  29. Osinubi A.A.A, Medubi L.J., Akang E.N., Sodiq L.K., Samuel, T.A., Kusemiju T., Osolu J., Madu D., Fasanmade O. A comparison of the anti-diabetic potential of Dribose-L-cysteine with insulin, and oral hypoglycaemic agents on pregnant rats. Toxicology Reports2018, (5):832-838.
  30. Emokpae O, Ben-Azu B, Ajayi AM, Umukoro S. D-Ribose-L-cysteine attenuates lipopolysaccharide-induced memory deficits through inhibition of oxidative stress, release of 9 proinflammatory cytokines, and nuclear factor-kappa B expression in mice. NaunynSchmiedeberg’s Archives of Pharmacology,07 January 2020.
  31. Kader T., Porteous M., Jones G., Dickerhof N., Narayana V.K., Taraknath S., McCormick S.P.A. Ribose-cysteine protects against the development of atherosclerosis in apoE-deficient mice. PLoS ONE,15(2):e0228415. 02 21 2020.
  32. Emokpae O, Ben-Azu B, Ajayi AM, Umukoro S. D-ribose-L-cysteine enhances memory task, attenuates oxidative stress and acetyl-cholinesterase activity in scopolamine amnesic mice. PLoS ONE,15(2)Drug Dev Res., March 11, 2020;1-8
  33. Amponsah S.K., N’guessan B.B, Akandawen, A.A., Agboli S.Y., Danso, E.A., Opuni K.F.M., Asiedu-Gyekye I.J., Appiah-Opong, R. Effect of Cellgevity Supplementation on Selected Rat Liver Cytochrome P450 Enzyme Activity and Pharmacokinetic Parameters of Carbamazepine. Evidence-Based Complementary and Alternative Medicine. Volume 2020(July 3), Article ID: 7956493, 8 pages.
  34. Okoh, L., Ajayi, A.M., Ben-Azu, B., Akinluyi, E.T., Emokpae, O., Umukoro, S. D-Ribose-L-Cysteine exhibits adaptogenic-like activity through inhibition of oxidoinflammatory responses and increased neuronal caspase-3 activity in mice exposed to unpredictable chronic mild stress.Molecular Biology Reports. 2020 47:7709-7722
  35. Medubi, L.J., Nwosu, N.C., Medubi, O.O., Lawal, O.R., Ama, C., Kusemiju, T.O., Osinubi, A.A.A. Increased de novo glutathione production enhances sexual dysfunctions in rats subjected to paradoxical sleep deprivation.JBRA Assisted reproduction. September 30, 2020; 1-8.
  36. Ogunlade, B., Gbotolorun S.C., Ogunlade, A.A. D-Ribose-L-Cysteine modulates lead acetateinduced hematobiochemical alterations, hormonal imbalance, and ovarian toxicity in adult female Wistar rats. Drug and Chemical Toxicology. November 7, 2020; 1-8.
  37. Ogunlade, B., Fidelis, O.P., Afolayan, O.O., Agie, J.A. Neurotherapeutic and antioxidant response of D-Ribose-L-Cysteine nutritional dietary supplements on Alzheimer-type hippocampal neurodegeneration induced by cuprizone in adult male wistar rate model. Food and Chemical Toxicology. November 11, 2020; 1-9.